In SCCM 2012 there can be more than one active Management Point per site.
The agent will automatically resolveĀ this list and handle the assignment dynamically.

Sometimes when the MP has been installed after for example the Reporting RoleĀ and WSUS the Inboxes path is not correctly set in the registry.

The problem lies in that smsexec can not process the files and forward these to the primary Site and then to SQL.

PROBLEM:

Missing from registry are the Key and the subvalues under:
[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\SMS\MPFDM\Inboxes]

Subsequent are the MPFDM hive located wrongly under the Wow6432Node node.

SOLUTION:
Remove MP, WSUS and other roles applicable and add the MP role first.
Check that Inboxes are correctly set in the registry.